The short answer is NO!
A new study from the Institute of Psychiatry, Psychology, and Neuroscience (IoPPN) at King’s College London, in association with COMPASS Pathways, has demonstrated that psilocybin can be securely managed at portions of either 10mg or 25mg in healthy people.
The study, distributed in the Journal of Psychopharmacology, is a fundamental initial phase in exhibiting the security and plausibility of psilocybin — a hallucinogenic medication disconnected from the Psilocybe mushroom — for use inside controlled settings close by talking treatment as a likely treatment for a scope of psychological well-being conditions, including treatment-safe sorrow (TRD) and PTSD.
Current treatment choices for these circumstances are inadequate or successful for some individuals, coming about in a huge neglected need. Early research has shown potential for psilocybin treatment to treat these gatherings, yet no preliminaries have been embraced at the scale required for administrative endorsement to make the treatment accessible.
The test is the first of its sort to examine the concurrent organization of psilocybin completely. 89 healthy members with no new (in no less than 1 year) utilization of psilocybin were enlisted. 60 people were haphazardly picked to get either a 10mg or 25mg portion of psilocybin in a controlled climate. Furthermore, all members were furnished with coordinated help from prepared psychotherapists. The leftover 29 members went about as the benchmark group and got a placebo treatment, likewise with mental help.
Members were firmly observed for six to eight hours following the organization of psilocybin and afterward followed up for 12 weeks. During this time, they were evaluated for various potential changes, including sustained attention, memory, and planning, as well as their capacity to handle feelings.
National Institute for Health Research Clinical Scientist Dr. James Rucker, the review’s lead creator from King’s IoPPN and privileged advisor specialist at South London, and that’s what Maudsley NHS Foundation Trust says “his rigorous study is an important first demonstration that the simultaneous administration of psilocybin can be explored further. If we think about how psilocybin therapy (if approved) may be delivered in the future, it’s important to demonstrate the feasibility and the safety of giving it to more than one person at the same time, so we can think about how we scale up the treatment. This therapy has promise for people living with serious mental health problems, like treatment-resistant depression (TRD) and PTSD. They can be extremely disabling, distressing, and disruptive, but current treatment options for these conditions are ineffective or partially effective for many people.”
Throughout the review, there were no cases of anybody pulling out from the concentrate because of an unfriendly occasion and no steady patterns to propose that both of the psilocybin portions had any short-or long haul adverse consequences for members.
Teacher Guy Goodwin, Chief Medical Officer, COMPASS Pathways, says that “this study was an early part of our clinical development program for COMP360 psilocybin therapy. It explored the safety and feasibility of simultaneous psilocybin administration, with 1:1 support, in healthy participants and provided a strong foundation to which we have now added positive results from our phase IIb trial in 233 patients with TRD and our open-label study of patients taking SSRI antidepressants alongside psilocybin therapy. We are looking forward to finalizing plans for our phase III program, which we expect to begin in Q3 2022.”
The specialists have since finished Phase II of the review, which has investigated the adequacy and wellbeing of psilocybin in individuals living with TRD and PTSD, and are breaking down the information.
Stay tuned for the results!